Prognostic factors in MGUS

Dátum: 10.01.2009 10:40
Vec: Mnohopocetný myelóm


Prognostic factors in monoclonal gammopathy of undetermined significance

Federico Sackmann, Miguel Arturo Pavlovsky, Claudia Corrado, Marco Pizzolato, Mariel Alejandre, Santiago Pavlovsky

Haematologica. 2008 Jan; 93:(1)153-154


ABSTRAKT

A retrospective evaluation of 285 patients with monoclonal gammopathy of undetermined significance was performed to identify variables associated with progression, actuarial progression free survival (PFS) and overall survival (OS). Three variables, level of uninvolved immunoglobulins (HR 4.98, CI95% 2 – 12.4, p=0.0006), monoclonal protein concentration (HR 4.04, CI95% 1.6–10.34, p=0.004), and erythrosedimentation rate (HR 3.94, CI95% 1.33–11.6, p=0.01), showed independent prognostic significance. With a median follow-up of 66 months (range 6–378), PFS and OS at 10 years were 89% and 91% respectively.

pozrieť článok






Tento článok je z Slovenský hematolologický portál
http://www.hematology.sk

URL tohoto článku je:
http://www.hematology.sk/modules.php?name=News&file=article&sid=262